Effective assassin guide

Damage
The skills in the table on assassin attack chain quick reference are sorted by damage (and cost) within attributes. So Palm Strike and either Nine Tails Strike or Critical Strike have the highest damage (without considering the effects of other skills )

Specific Builds: A/any Hexer A/any Self Enchanter

Kiting
shadow step

Energy Management
Black Lotus Strike will gain the Assassin some energy if the target is Hexed (say, by Impale in this build). Golden Lotus Strike will gain the Assassin some energy if the Assassin is enchanted.

Condition and Hex Removal
Monk Protection Prayers will Mend an Ailment (remove a condition and maybe heal) and the No Attribute Monk skill will Remove a Hex.

The Mesmer Inspiration Magic Signet Hex Eater and Inspired Hex will remove a hex and gain some energy. Shatter Hex is a Mesmer Domination skill that will remove a hex and deal damage to nearby foes.

Condition Transfer
The Necromancer No Attribute skill Plague Touch will remove a condition and Transfer it to a touched opponent.