Margonite

Margonites are a species in the bestiary of Guild Wars, expected to be featured in the Nightfall campaign.

Concept art included with the Guild Wars Nightfall Prerelease Bonus Pack shows that they are humanoid, but with 4 arms or 2 arms plus 2 wings respectively. They seem to have 6 eyes, but hide their face behind a mask/helmet. Fins and webs on their body imply that they were originally amphibeous creatures, however it is also possible that they may have been human before their 'horrific transformation'.

Margonites in the Crystal Desert
The Margonites were an ancient seafaring civilization who visited the Crystal Desert 'hundreds of years' before the current time, and predated the Elonians.

In their attempts to achieve Ascension, they constructed towers in order to ascend to the gods, not realizing that it is not by physical means one may ascend. Like all others, the Margonites failed.

At the time the Margonites attempted Ascension, the Crystal Desert was mostly covered in water. Being a seafaring civilization, their architecture is primarily constructed out of (or built to resemble) parts of old ships. Their greatest concentration of settlements appears to have been in the southeast corner of the Crystal Desert near Thirsty River and Destiny's Gorge.

It has recently been revealed that, roughly a thousand years ago, the Margonites worshipped an unnamed evil sixth god, who blessed them with horrific transformations that granted them awesome power, and waged war against the followers of the Five Gods of Tyria. The epic battle between the Margonites and the followers of the Five Gods devastated northern Elona, creating the Crystal Desert. It can be inferred that the Margonites sought Ascension to fight against the Five Gods and their followers.