Afflicted Soul Explosion

Description
The damage caused by the Explosion is scaled by the difference between your level and the monster's level. A low level Afflicted will explode for 40+ damage, while a level 24 Afflicted will explode for over 140 damage. This is especially painful with Afflicted bosses because they deal double damage as bosses and already deal high damage because of their level.

Strategy
If you find yourself near an Afflicted about to die, move away quickly if you are low on health. Since warriors usually have high health they generally don't need to move, an exception is if you are have a high death penalty on you in which case warriors are also likely to be killed by the explosion.

If you are low on health and are near an Afflicted with full health, you should be fine (ignoring the damage you're already receiving if the Afflicted is targeting you). However, if you have a spiker or nuker on the team, make sure you have time to escape before they unload the damage.