Virulence

Acquisition
Signet of Capture:
 * Unthet Rotwood (Frozen Forest)
 * The following capture location is no longer available, but could be captured during the Factions Preview Event
 * Mukesh the Merciless (Nebo Terrace only during Establish the Kurzick Settlement)

Usage Notes

 * Virulence is popular with PvP Mesmers/Necromancers (see Me/N Fragility Spiker). Focusing upon dealing a large amount of damage quickly to a single target, the skills used are: Fragility, Phantom Pain, Shatter Delusions, and Virulence. Fragility causes a large amount of damage whenever the hexed foe receives or recovers from a new condition. Once Phantom Pain is active, use Shatter Delusions to remove the hex; using that combo causes a Deep Wound, and then cast Virulence to induce 3 more conditions.  All are short lived, causing a large spike in damage to a single target.
 * If playing pure necro, you can set this skill up with Enfeeble, Enfeebling Blood, or Enfeebling Touch to give the target Weakness then follow with Virulence to add Poison and Disease. If you follow this with Vile Miasma, you can give a foe an easy -10 degen.