Amnoon Oasis to "Desert Tour"

From Amnoon Oasis to Augury Rock
This is an extremely hard run, as long as you don't go wildly off route, there are few-to-no enemies who can slow you down or knock you down, as well as no narrow areas where enemies can block you in and keep you from proceeding. The only things needing consideration is the fact that there are a good few beetles around near the end of the trip which put down traps, keeping an eye out for these or keeping to safe areas could be important.

The teleporter can often be difficult to run past, so having someone distract the locals while you activate the teleporter, or just being quick about it, may be preferred.

Once past the canyon, by teleporter, it's a straightforward run, the patrols that can't simply be avoided can easily be outdistanced since none of them have speed-enhancing skills. The only possibly problem is the one or two Hydras in the area, who can knock you down and hammer you good with their Meteor spell.

After you use the first teleporter, you may be able to save a few seconds of time by using a second teleporter a short distance to the southeast of your arrival point after using the first one.

On the very last stretch of the journey the only threat, as noted, are Rockshot Devourers who drop down Flame Traps and Dust Traps all over the place.