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It can be used with a R/W, especially one using Barrage, as the Ranger can spam this skill with a small investment in Tactics to aid the backline casters, should aggro break off the tank.
It also works well on D/W Dervishes with a few points in Tactics because their scythe attack can gain up to 3 adrenaline per swing.
Using "Watch Yourself" with a P/W Paragon, works well because it can affect echos like Mending Refrain.
Even with a small investment in Tactics this can be useful as a support skill, for example the +10 armor bonus at level 4 Tactics is equivalent to a caster character having the same AL as a Ranger.