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Disease visual.jpg
In-game description:


Condition. While suffering from this ailment, you lose Health over time. Disease is contagious between creatures of the same kind.

Characters inflicted with disease suffer 4 health degeneration (8 health each second).


  • Disease is contagious and will infect other adjacent creatures of the same species.
  • Visually, a diseased character is easily recognised via the swirling green gases and flies surrounding him.
  • Disease turns the target's health bar green. In PvE, it can spread from human foes such as Corsairs or the Jade Brotherhood to players characters, heroes, and henchmen. In PvP, all characters and NPCs aside from pets, Juggernauts, and Turtles are considered to be the same type of creature.
  • Disease can only affect fleshy creatures.
  • If you cast a spell causing Disease as a necromancer and that creature spreads it back to you, using Plague Touch, Plague Signet, or Plague Sending while that creature is still close to you will not cause the Disease to immediately return to you, even though it meets the requirements of spreading.


Name Target Duration Stats Notes Skill type Attr Cam
Putrid Flesh.jpg Putrid Flesh Foes near minion 5...13s
    10 Energy.png ¼ Activation.png  
Destroy minion Spell NecromancerDeath N
Rotting Flesh.jpg Rotting Flesh Foe 10...22s
    15 Energy.png 3 Activation.png 3 Recharge.png
Spell NecromancerDeath C
Tainted Flesh.jpg Tainted Flesh Ally 3...13s
    5 Energy.png 1 Activation.png  
Remove Disease, for +duration target is immune to disease & foes striking target become diseased Elite Enchantment Spell NecromancerDeath C
Virulence.jpg Virulence Foe 3...13s
    5 Energy.png 1 Activation.png 15 Recharge.png
If already suffering from a condition, give Disease, Poison, & Weakness Elite Spell NecromancerDeath P
Avatar of Grenth.jpg Avatar of Grenth Adjacent foes 3s
    5 Energy.png 2 Activation.png 20 Recharge.png
Whenever a Dervish enchantment is lost. You deal dark damage, steal 0...10 life on hit, and are immune to disease. Elite Form DervishMyst N
Mystic Corruption.jpg Mystic Corruption Adjacent foes 1...2s
    10 Energy.png   10 Recharge.png
Duration is doubled if you are enchanted. Removes disease on end. Flash Enchantment Spell DervishMyst N

PvE only[]

Name Target Duration Stats Notes Skill type Attr Cam
Radiation Field.jpg Radiation Field Foes in the area 12...20s
    15 Energy.png 2 Activation.png 12 Recharge.png
after 4...6 seconds of -2...6 health degen Ward Spell Asura E
Signet of Infection.jpg Signet of Infection Foe 13...20s
        1 Activation.png 10 Recharge.png
If target foe is Bleeding Signet Vanguard E

Related skills[]

See also[]

Bleeding.jpg Bleeding Blind.jpg Blind Burning.jpg Burning Cracked Armor.jpg Cracked Armor Crippled.jpg Crippled Dazed.jpg Dazed Deep Wound.jpg Deep Wound Disease.jpg Disease Poison.jpg Poison Weakness.jpg Weakness