Pain Titans are spawned from slain Titan Abominations. When slain, a Pain Titan will spawn two Madness Titans. Pain Titans are vulnerable to Lightbringer's Gaze, but, despite their appearance, they are not fleshy creatures, making them immune to Bleeding, Poison and Disease.
- Pain Titans spawned from slain Titan Abominations will not drop loot, but will yield experience and, with the appropriate bounty, Lightbringer points.
- Oddly, Pain Titans have exceptionally low energy storage, despite their use of Mind Blast. This is not true in Hard Mode, where they have 20 in all attributes.