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This skill can be useful even at zero Curses, due to the large sacrifice it makes. Certain skills, such as Grenth's Balance, Ravenous Gaze, and Blood Drinker, are more effective with low health.
Although this spell seems at first like a very expensive way to remove enchantments since most enchantment removal tends to affect the target more than the caster, bear in mind that this spell has a low cost (in spite of the sacrifice), quick recharge time and quick casting speed making it a very useful general purpose enchantment remover since you almost invariably will be able to use it in a pinch.